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Role of IFNγ in Allograft Tolerance Mediated by CD4+CD25+ Regulatory T Cells by Induction of IDO in Endothelial Cells

✍ Scribed by P. Thebault; T. Condamine; M. Heslan; M. Hill; I. Bernard; A. Saoudi; R. Josien; I. Anegon; M. C. Cuturi; E. Chiffoleau

Book ID
114804516
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
497 KB
Volume
7
Category
Article
ISSN
1600-6135

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In mouse liver transplantation, tolerance is readily inducible. Recent studies have revealed that CD25+ CD4+ regulatory T cells play an important role in regulating various immune responses, including transplant tolerance. However, the contribution of these cells to tolerance in mouse liver transpla