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Role of Glutathione and Other Thiols in Cellular Response to Radiation and Drugs

✍ Scribed by Biaglow, John E.; Varnes, Marie E.; Epp, Edward R.; Clark, Edward P.; Tuttle, Stephen W.; Held, Kathryn D.


Book ID
111650399
Publisher
Informa plc
Year
1989
Tongue
English
Weight
491 KB
Volume
20
Category
Article
ISSN
0360-2532

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Three ACNU-resistant sublines (Ri, R, and Rid. from rat glioma 9L cells showed cross-resistance to vinblastine, adriamycin, and VP-16. Among these, the R, subline also acquired radioresistance under aerobic conditions. Total glutathione levels in these sublines were elevated 2-to 3-fold. Treatment o