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Role of GABA-ergic and serotonergic systems in the anxiolytic-like mechanism of action of a 5-HT-moduline antagonist in the mouse elevated plus maze

✍ Scribed by Florence Clénet; Martine Hascoët; Gilles Fillion; Hervé Galons; Michel Bourin

Book ID
116283784
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
492 KB
Volume
158
Category
Article
ISSN
0166-4328

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Previous studies have shown that (\*) S 20244 (8-(4-[N-(5-methoxychroman-3-yl) N-propylamino] butyl) 8-azaspiro[4,5]decane-7,9 dione) and its isomers ( + ) S 20499 and (-) S 20500 are full agonists at 5-HT,, receptors. In the present study, the effects of these three compounds were investigated in t