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Anxiolytic-like profile of p-MPPI, a novel 5HT1A receptor antagonist, in the murine elevated plus-maze

✍ Scribed by B.-J. Cao; R. J. Rodgers


Publisher
Springer
Year
1997
Tongue
English
Weight
235 KB
Volume
129
Category
Article
ISSN
0033-3158

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Anxiolytic properties of (+) s 20499, a
✍ Peter F. Curle; Elisabeth Mocaer; Pierre Renard; BΓ©atrice Guardiola πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 854 KB

Previous studies have shown that (\*) S 20244 (8-(4-[N-(5-methoxychroman-3-yl) N-propylamino] butyl) 8-azaspiro[4,5]decane-7,9 dione) and its isomers ( + ) S 20499 and (-) S 20500 are full agonists at 5-HT,, receptors. In the present study, the effects of these three compounds were investigated in t