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Role of Erythropoietin in 7,12-Dimethylbenz(a)anthracene Induction of Acute Chromosome Aberration and Leukemia in the Rat

✍ Scribed by Taketoshi Sugiyama

Book ID
123650654
Publisher
National Academy of Sciences
Year
1971
Tongue
English
Weight
643 KB
Volume
68
Category
Article
ISSN
0027-8424

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The 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat leukemia model enables scientists to analyze cells altered by carcinogens at various stages of leukemogenesis. We have reported that a consistent type of point mutation, A→T transversion at the second base in codon 61 of the N-ras gene, was prese