Chromosome Abnormality in Rat Leukemia Induced by 7,12-Dimethylbenz[a]anthracene
β Scribed by Sugiyama, T.; Kurita, Y.; Nishizuka, Y.
- Book ID
- 121179853
- Publisher
- American Association for the Advancement of Science
- Year
- 1967
- Tongue
- English
- Weight
- 628 KB
- Volume
- 158
- Category
- Article
- ISSN
- 0036-8075
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## Abstract The banding pattern of DMBAβinduced leukemias in C57BL/6 mice revealed a very constant chromosome pattern: the presence of trisomy 15 in almost all leukemic cells. This finding strongly suggests that chromosome 15 trisomy is the first detectable specific chromosome change associated wit
## Abstract This report describes morphological transformations observed approximately 6 weeks after treatment of Rauscher leukemia virus (RLV) infected rat embryo (RE) cells with various levels of 7,12βDimethylbenz(a)βanthracene (DMBA) for 7 days. Uninfected cells treated with DMBA and RLVβinfecte