Role of drug metabolism in drug research and development: Pharmaceutical chemistry aspects
โ Scribed by Kenneth R. Helmlich
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- English
- Weight
- 377 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
โฆ Synopsis
Pharmacokinetic data obtained jointly by the drug metabolism group and the pharmaceutical chemist are essential to the selection of the proper dosage form for preclinical and Phase I studies. Subsequent biopharmaceutic studies aid in the development of alternate dosage forms and in devising suitable in uirro procedures for ensuring batch-to-batch reproducibility in production. Keyphrases Drug metabolism-role in drug research and development, symposium 0 Biopharmaceutics-development of dosage forms 0 Pharmaceutical chemists-selection of dosage forms for preclinical and Phase 1 studies 0 Dosage form development-role of drug metabolism group and pharmaceutical chemist
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Data from the rapid systematic study of the fate of a new drug in rats and dogs can aid the design of pharmacological and safety tests and can provide a basis for biopharmaceutic and Phase I clinical trials. Keyphrases Drug metabolism-role in drug research and development, symposium Biopharmaceutics
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