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Role of Cytokines in the Pathogenesis of Autoimmune Diabetes Mellitus

✍ Scribed by Alex Rabinovitch; Wilma L. Suarez-Pinzon


Book ID
111548721
Publisher
Springer
Year
2003
Tongue
English
Weight
90 KB
Volume
4
Category
Article
ISSN
1389-9155

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Correlation studies between cytokines expressed in islets and autoimmune diabetes development in NOD mice and BB rats have demonstrated that ␀-cell destructive insulitis is associated with increased expression of proinflammatory cytokines (IL-1, TNF␣, and IFN␣) and type 1 cytokines (IFNβ₯, TNF␀, IL-2