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Role of Conserved Active Site Residues in Catalysis by Phospholipase B1 from Cryptococcus neoformans †

✍ Scribed by Jones, Peter M.; Turner, Kylie M.; Djordjevic, Julianne T.; Sorrell, Tania C.; Wright, Lesley C.; George, Anthony M.

Book ID
126046552
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
668 KB
Volume
46
Category
Article
ISSN
0006-2960

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Understanding the role of active-site residues in enzymatic catalysis is of fundamental importance for a microscopic description of the catalytic mechanism, but also for the design of effective enzyme mimics or improvement of existing enzymes (or abzymes) for catalyzing chemical reactions. Site-dire