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Role of connective tissue growth factor in profibrotic action of transforming growth factor-β: A potential target for preventing renal fibrosis

✍ Scribed by Hideki Yokoi; Akira Sugawara; Masashi Mukoyama; Kiyoshi Mori; Hisashi Makino; Takayoshi Suganami; Tetsuya Nagae; Kensei Yahata; Yuriko Fujinaga; Issei Tanaka; Kazuwa Nakao

Book ID
114463302
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
123 KB
Volume
38
Category
Article
ISSN
0272-6386

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Skin fibrotic disorders are understood to develop under the influence of some growth factors, such as transforming growth factor-beta (TGF-␤), basic fibroblast growth factor (bFGF), or connective tissue growth factor (CTGF). To establish an appropriate animal model of skin fibrosis by exogenous appl