## Abstract Insulin‐like growth factor binding protein‐3 (IGFBP‐3) has been proposed to mediate the growth inhibitory effects of transforming growth factor (TGF)‐β in breast and prostate cancer cells. Both TGF‐β and exogenous IGFBP‐3 inhibit DNA synthesis in Mv1 mink lung epithelial cells (CCL64).
✦ LIBER ✦
Connective tissue growth factor mediates the profibrotic effects of transforming growth factor-β produced by tubular epithelial cells in response to high glucose
✍ Scribed by Tatsuya Kobayashi; Tsutomu Inoue; Hirokazu Okada; Tomohiro Kikuta; Yoshihiko Kanno; Takashi Nishida; Masaharu Takigawa; Takeshi Sugaya; Hiromichi Suzuki
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 438 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1342-1751
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The relationship between the expression of selected oncogenes having different modes of action and the loss of the capacity t o respond in vitro to transforming growth factor+ I (TGF-P I) was analyzed in human mammary epithelial cells (MEC). Primary MEC cultures from healthy donors and the spontaneo