✦ LIBER ✦

Role of cell-cycle regulators in lung cancer

✍ Scribed by Mario Caputi; Giuseppe Russo; Vincenzo Esposito; Alessandro Mancini; Antonio Giordano

Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 336 KB
Volume: 205
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.20424

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Lung cancer is the leading cause of cancer death worldwide. Histologically, 80% of lung cancers are classified as non‐small‐cell lung cancer (NSCLC), and the remaining 20% as small‐cell lung cancer (SCLC). Lung carcinoma is the result of molecular changes in the cell, resulting in the deregulation of pathways controlling normal cellular growth, differentiation, and apoptosis. This review summarizes some of the most recent findings about the role of cell‐cycle proteins in lung cancer pathogenesis and progression. © 2005 Wiley‐Liss, Inc.

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