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Role of caspases in acetaminophen-induced liver injury

✍ Scribed by Hartmut Jaeschke; Cathleen Cover; Mary Lynn Bajt

Book ID: 116718278
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 330 KB
Volume: 78
Category: Article
ISSN: 0024-3205
DOI: 10.1016/j.lfs.2005.07.003

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## Abstract Neutrophils and macrophages infiltrate after acetaminophen (APAP)‐induced liver injury starts to develop. However, their precise roles still remain elusive. In untreated and control IgG‐treated wild‐type (WT) mice, intraperitoneal APAP administration (750 mg/kg) caused liver injury incl