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The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice

✍ Scribed by Brittany V. Martin-Murphy; Michael P. Holt; Cynthia Ju


Book ID
119381810
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
709 KB
Volume
192
Category
Article
ISSN
0378-4274

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## Abstract Neutrophils and macrophages infiltrate after acetaminophen (APAP)‐induced liver injury starts to develop. However, their precise roles still remain elusive. In untreated and control IgG‐treated wild‐type (WT) mice, intraperitoneal APAP administration (750 mg/kg) caused liver injury incl