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Potential roles of hepatic heat shock protein 25 and 70i in protection of mice against acetaminophen-induced liver injury

โœ Scribed by Isao Sumioka; Tatsuya Matsura; Masachika Kai; Kazuo Yamada


Book ID
116717287
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
192 KB
Volume
74
Category
Article
ISSN
0024-3205

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In studies designed to simulate a clinical observation in which an individual became tolerant to normally lethal doses of acetaminophen (APAP), mice were pretreated with increasing doses of APAP for 8 days and challenged on day 9 with normally supralethal doses of APAP. These animals developed minim