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296 Role of Sphingosine Kinase-2 in Acetaminophen-Induced Liver Injury

✍ Scribed by Rehman, Hasibur; Liu, Qinlong; Krishnasamy, Yasodha; Haque, Khujista; Shi, Yanjun; Saggu, Shalini; Lemasters, John J.; Smith, Charles D.; Zhong, Zhi

Book ID
122260030
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
82 KB
Volume
142
Category
Article
ISSN
0016-5085

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## Abstract Neutrophils and macrophages infiltrate after acetaminophen (APAP)‐induced liver injury starts to develop. However, their precise roles still remain elusive. In untreated and control IgG‐treated wild‐type (WT) mice, intraperitoneal APAP administration (750 mg/kg) caused liver injury incl