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Role of Caco-2 Cell Monolayers in Prediction of Intestinal Drug Absorption

โœ Scribed by Shah, P.; Jogani, V.; Bagchi, T.; Misra, A.


Book ID
120347728
Publisher
American Institute of Chemical Engineers
Year
2006
Tongue
English
Weight
449 KB
Volume
22
Category
Article
ISSN
8756-7938

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Permeability coefficients across monolayers of the human colon carcinoma cell line Caco-2, cultured on permeable supports, are commonly used to predict the absorption of orally administered drugs and other xenobiotics. This protocol describes our method for the cultivation, characterization and dete