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Role of AML1/Runx1 in the pathogenesis of hematological malignancies

✍ Scribed by Mineo Kurokawa; Hisamaru Hirai

Book ID
108582207
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
603 KB
Volume
94
Category
Article
ISSN
1347-9032

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## Abstract __AML1__/__RUNX1__, located on chromosome band 21q22, is one of the most important hematopoietic transcription factors. __AML1__ is frequently affected in leukemia and myelodysplastic syndrome with 21q22 translocations. Recently, __AML1__ mutations were found in adult hematologic malign

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