𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes

✍ Scribed by Florence Joannard; Mary Rissel; David Gilot; Alan Anderson; Luz Orfila-Lefeuvre; André Guillouzo; Azzedine Atfi; Dominique Lagadic-Gossmann

Book ID
119378207
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
359 KB
Volume
161
Category
Article
ISSN
0378-4274

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Docosahexaenoic acid downregulates pheno
Docosahexaenoic acid downregulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes via the c-Jun NH2-terminal kinase mitogen-activated protein kinase pathway
✍ Chia-Yang Lu; Chien-Chun Li; Kai-Li Liu; Chong-Kuei Lii; Haw-Wen Chen 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 840 KB

## Abstract Mitogen‐activated protein kinase (MAPK) pathways play central roles in the transduction of extracellular stimuli into cells and the regulation of expression of numerous genes. Docosahexaenoic acid (DHA) was shown to be involved in the regulation of expression of drug metabolizing enzyme

Effect of phenytoin on cytochrome P450 2
Effect of phenytoin on cytochrome P450 2B mRNA expression in primary rat astrocyte cultures
✍ Bernd Ibach; Kurt Appel; Peter Gebicke-Haerter; Ralf Peter Meyer; Thomas Friedbe 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 242 KB 👁 2 views

Studies on cytochrome P450 2B (CYP2B) in the brain have essentially been focused on protein characterization and regional distribution. Due to the high sequence homology between the closely related CYP2B1 and 2B2 isoforms and the low amounts of the corresponding mRNAs few efforts have been made to a