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DHA down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes by attenuating CAR translocation

✍ Scribed by Chien-Chun Li; Chong-Kuei Lii; Kai-Li Liu; Jaw-Ji Yang; Haw-Wen Chen


Book ID
113924197
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
535 KB
Volume
225
Category
Article
ISSN
0041-008X

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Docosahexaenoic acid downregulates pheno
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## Abstract Mitogen‐activated protein kinase (MAPK) pathways play central roles in the transduction of extracellular stimuli into cells and the regulation of expression of numerous genes. Docosahexaenoic acid (DHA) was shown to be involved in the regulation of expression of drug metabolizing enzyme