Background. Small cell lung cancer (SCLC) is distinguished from other histologic types of lung cancer by possessing a variety of neuroendocrine properties. Neuron-specific enolase (NSE) is the most frequently elevated tumor marker for patients with SCLC at diagnosis. To assess the value of neural ce
RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule
โ Scribed by Sarah Shigdar; Jia Lin; Yan Yu; Mile Pastuovic; Ming Wei; Wei Duan
- Book ID
- 108587035
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 650 KB
- Volume
- 102
- Category
- Article
- ISSN
- 1347-9032
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The purpose of this investigation was to determine the targeting potential of the murine monoclonal antibody (MAb) RNL-I for human small-cell lung cancer (SCLC) in a nude mouse model. RNL-I is preferentially reactive with SCLC and lung carcinoids, and was classified as a cluster-I MAb as defined by