## Abstract Cancer stem cells (CSCs) are similar to normal stem cells in their ability to selfβrenew and to generate large populations of more differentiated descendants. In contrast to the hierarchical organization that is presumed to be the prevalent mode of normal tissue homeostasis, phenotypic
The Epithelial-to-Mesenchymal Transition and Cancer Stem Cells: A Coalition Against Cancer Therapies
β Scribed by Brett G. Hollier; Kurt Evans; Sendurai A. Mani
- Publisher
- Springer US
- Year
- 2009
- Tongue
- English
- Weight
- 327 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1083-3021
No coin nor oath required. For personal study only.
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## Abstract We report here side population (SP) cells, a cancer stem cell enriched fraction from pancreatic cancer cell line, have enormous superior potential of the epithelial to mesenchymal transition (EMT), invasion, and metastasis. In an isolated SP cell culture, the cells rapidly expressed and