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Risk of Colorectal Cancer for Carriers of Mutations in MUTYH, With and Without a Family History of Cancer

✍ Scribed by Win, Aung Ko; Dowty, James G.; Cleary, Sean P.; Kim, Hyeja; Buchanan, Daniel D.; Young, Joanne P.; Clendenning, Mark; Rosty, Christophe; MacInnis, Robert J.; Giles, Graham G.; Boussioutas, Alex; Macrae, Finlay A.; Parry, Susan; Goldblatt, Jack; Baron, John A.; Burnett, Terrilea; Le Marchand, Loïc; Newcomb, Polly A.; Haile, Robert W.; Hopper, John L.; Cotterchio, Michelle; Gallinger, Steven; Lindor, Noralane M.; Tucker, Katherine M.; Winship, Ingrid M.; Jenkins, Mark A.

Book ID
121743936
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
647 KB
Volume
146
Category
Article
ISSN
0016-5085

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Cancer risks for monoallelic MUTYH mutat
Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer
✍ Aung Ko Win; Sean P. Cleary; James G. Dowty; John A. Baron; Joanne P. Young; Dan 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 157 KB 👁 2 views

## Abstract Cancer risks for a person who has inherited a __MUTYH__ mutation from only one parent (monoallelic mutation carrier) are uncertain. Using the Colon Cancer Family Registry and Newfoundland Familial Colon Cancer Registry, we identified 2,179 first‐ and second‐degree relatives of 144 incid