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Ring transformation of pyrimidines to pyridines. Synthesis of 4-alkylaminopyridin-2-ones by alkaline hydrolysis of 6-(2-dimethylaminovinyl)uracils

โœ Scribed by Kosaku Hirota; Yoshio Abe; Tetsuji Asao; Shigeo Senda; Yukio Kitade; Yoshifumi Maki


Book ID
112128966
Publisher
Journal of Heterocyclic Chemistry
Year
1988
Tongue
English
Weight
322 KB
Volume
25
Category
Article
ISSN
0022-152X

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Studies on uracils: synthesis of novel p
โœ P.J Bhuyan; H.N Borah; R.C Boruah ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 184 KB

The reaction of isoxazolo [3,4-d]pyrimidine 1 and cyanoolefins 2 in the presence of triethylamine (Et 3 N) as a catalyst afforded an unprecedented one-pot synthesis of biologically important pyrido [2,3-d]pyrimidine oxides 3 in excellent yields.