Rhodium-catalyzed ortho-alkylation of aromatic aldimines and ketimines via CH bond activation

✍ Scribed by Yeong-Gweon Lim; Jong-Soo Han; Seung-Sun Yang; Jong Han Chun

• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 108 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)00865-6

✦ Synopsis

The aldimines reacted with alkenes under a rhodium catalytic system, Rh[(coe) 2 Cl] 2 and Cy 3 P, to give mainly the double alkylated products with moderate to high yields. On the other hand, the ketimine 9 gave the mono alkylated product predominantly.