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Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia–lymphoma cells

✍ Scribed by Drexler, H G

Book ID
110053866
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
248 KB
Volume
12
Category
Article
ISSN
0887-6924

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## Abstract Cyclin and cyclin‐dependent kinase (a) complexes play important roles in modulating the cell cycle. The CDK inhibitors (a) inhibit the kinase activities of these complexes and block the cell cycle. The __p16__/multiple tumor suppressor (__MTS__) 1/inhibitor of CDK4 (__INK4__) a/__CDKN2_