Inactivation of p15(Ink4b) expression by promoter hypermethylation occurs in up to 80% of acute myeloid leukemia (AML) cases and is particularly common in the FAB-M2 subtype of AML, which is characterized by the presence of the RUNX1-ETO translocation in 40% of cases. To establish whether the loss o
Expression and regulation of G1 cell-cycle inhibitors (p16INK4A , p15INK4B, p18 INK4C, p19INK4D ) in human acute myeloid leukemia and normal myeloid cells
โ Scribed by Schwaller, J; Pabst, Th; Koeffler, H P; Niklaus, G; Loetscher, P; Fey, M F; Tobler, A
- Book ID
- 110053386
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 324 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0887-6924
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