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Reversible pH-dependent Conformational Change of Reconstituted Influenza Hemagglutinin

โœ Scribed by Suren A. Tatulian; Lukas K. Tamm

Book ID
115627449
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
224 KB
Volume
260
Category
Article
ISSN
0022-2836

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Binding of the fluorophore 1,1'-bis(4-anilino)naphthalene-5,5'-disulfonic acid (bis-ANS) to influenza virus A/PR 8/34 is strongly enhanced at low pH. Binding is accompanied by a significant increase in fluorescence intensity. The binding and the fluorescence increase are associated with the low-pH i