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Kinetics of the low pH-induced conformational changes and fusogenic activity of influenza hemagglutinin

✍ Scribed by Krumbiegel, M.; Herrmann, A.; Blumenthal, R.


Book ID
119410372
Publisher
Biophysical Society
Year
1994
Tongue
English
Weight
625 KB
Volume
67
Category
Article
ISSN
0006-3495

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Binding of the fluorophore 1,1'-bis(4-anilino)naphthalene-5,5'-disulfonic acid (bis-ANS) to influenza virus A/PR 8/34 is strongly enhanced at low pH. Binding is accompanied by a significant increase in fluorescence intensity. The binding and the fluorescence increase are associated with the low-pH i