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Conformational change of influenza virus hemagglutinin is sensitive to ionic concentration

✍ Scribed by Thomas Korte; Kai Ludwig; Qiang Huang; P. Sivaramakrishna Rachakonda; Andreas Herrmann


Publisher
Springer
Year
2007
Tongue
English
Weight
320 KB
Volume
36
Category
Article
ISSN
1432-1017

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Binding of the fluorophore 1,1'-bis(4-anilino)naphthalene-5,5'-disulfonic acid (bis-ANS) to influenza virus A/PR 8/34 is strongly enhanced at low pH. Binding is accompanied by a significant increase in fluorescence intensity. The binding and the fluorescence increase are associated with the low-pH i