Retrovirus-mediated gene transfer into human hematopoietic stem cells
✍ Scribed by P. Chu; C. Lutzko; A. Keith Stewart; I. D. Dubé
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 384 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0946-2716
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## Abstract ## Background Retrovirus‐mediated gene transfer is a useful technology in studying the biology of hematopoietic stem cells (HSCs) as well as in developing gene therapy products for a variety of human diseases. One of the most important factors determining the success of these studies i
Numerous incremental technological improvements have occurred recently in the application of therapeutic retrovirus-mediated gene transfer into hematopoietic stem cells (HSCs). Improved transduction efficiencies are now reaching levels that may correct some inherited or acquired disorders. Novel ret