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Gene transfer into hematopoietic cells

✍ Scribed by A. W. Nienhuis


Publisher
Springer
Year
1996
Tongue
English
Weight
95 KB
Volume
38
Category
Article
ISSN
1269-3286

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## Abstract ## Background A paucity of coxsackie adenovirus receptor (CAR) hampers the adenovirus serotype 5 (Ad5)‐based vector‐mediated gene transfer into malignant hematopoietic cells. Fiber‐retargeted adenoviral vectors with species B tropism can potentially bypass the CAR requirement and facil