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Retroviral Vectors for Use in Human Gene Therapy for Cancer, Gaucher Disease, and Arthritis

✍ Scribed by PAUL D. ROBBINS; HIDEAKI TAHARA; GUNHILD MUELLER; GREG HUNG; ALFRED BAHNSON; LAURENCE ZITVOGEL; JOANNA GALEA-LAURI; TOYA OHASHI; KEN PATRENE; SALLIE S. BOGGS; CHRISTOPHER H. EVANS; JOHN A. BARRANGER; MICHAEL T. LOTZE


Book ID
119870039
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
1009 KB
Volume
716
Category
Article
ISSN
0890-6564

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## Abstract Abstract: We explored the possibility of entrapping retroviral vector producing cells (VPC) within porous 3D matrix to induce a local and sustained release of viral particles to the malignant milieu. PA317/STK, which constantly shed reroviral vectors, was used to transduce cancer cells