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Use of the 2A sequence from foot-and-mouth disease virus in the generation of retroviral vectors for gene therapy

✍ Scribed by de Felipe, P; Martín, V; Cortés, M L; Ryan, M; Izquierdo, M

Book ID
110038345
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
291 KB
Volume
6
Category
Article
ISSN
0969-7128

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Because of the distinct ability of retroviruses to integrate into the target cell genome and thus achieve long-term expression, retrovirus vectors hold great promise for stable gene transfer. Such vectors derived from human immunodeficiency retroviruses (HIVs) and other lentiviruses are envisioned t