Retroviral vectors for gene therapy of Duchenne muscular dystrophy
β Scribed by A. Fassati
- Publisher
- Springer Milan
- Year
- 2000
- Tongue
- English
- Weight
- 31 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1590-1874
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## Abstract Mutations in the dystrophin gene cause an Xβlinked genetic disorder: Duchenne muscular dystrophy (DMD). Stem cell therapy is an attractive method to treat DMD because a small number of cells are required to obtain a therapeutic effect. Here, we discussed about multiple types of myogenic
## Abstract ## Background Retroviral vectors (RVs) constitute one of the preferred gene therapy tools against inherited and acquired diseases. Development of scaleable downstream processes allowing purification under mild conditions and yielding viral preparations with high titer, potency and puri