Gene therapy for duchenne dystrophy
โ Scribed by Andrew G. Engel
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 240 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The letter by on the theoretical expectations for deletional mutations in Duchenne muscular dystrophy (DMD) is very misleading. The authors base al1 of their arguments and calculations on the hypothesis that, in DMD, deletions occur exclusively or aimost exclusively by homologous recombination, and
## To the Editor: In a population, when equilibrium between mutation and selection is reached, a fraction (x) of individuals affected by an X-linked recessive lethal disorder is due to new mutations [Haldane, 19351. Being p, the mutation rate in female germ cells, and v, the mutation rate in male
The aim of the present study was to assess the impact of genetic counseling in young women at risk to have Duchenne muscular dystrophy (DMD) children prior to childbearing. A total of 263 potential DMD carriers, who had had genetic counseling and were given different genetic risks, were included in