## Abstract ## Objective: Preclinical evidence indicates that gene transfer to the dorsal root ganglion using replication‐defective herpes simplex virus (HSV)‐based vectors can reduce pain‐related behavior in animal models of pain. This clinical trial was carried out to assess the safety and explo
✦ LIBER ✦
Gene therapy for muscular dystrophy reaches human clinical trial
✍ Scribed by Paula R. Clemens; Saman Eghtesad; Daniel P. Reay
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 388 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
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Background Assessing the biological activity and clinical ef®cacy of gene therapy is critically important in cystic ®brosis (CF). It is widely accepted that clinical testing using surrogate markers including pulmonary function will be useful in assessing clinical ef®cacy. One problem with pulmonary