Rethinking the molecular definition of regulatory T cells
β Scribed by Shohei Hori
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 91 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Adult Tβcell leukemia/lymphoma (ATLL) patients are highly immunocompromised, but the underlying mechanism responsible for this state remains obscure. Recent studies demonstrated that __FOXP3__, which is a master control gene of naturally occurring regulatory T (Treg) cells, is expressed
## Abstract There has been accumulating evidence that CD4^+^CD25^+^ FoxP3 expressing regulatory T cells (Treg) are highly concentrated in tumors, thereby fostering an immuneβprivileged microenvironment. Some studies have shown that Tβcell receptor (TCR) stimulation can convert conventional T cells
## Abstract Since entering the immunological stage several decades ago, regulatory T cell biology has been realized as fundamentally important in the prevention of autoimmune conditions, induction of transplant tolerance and the immune response to cancer. The role of regulatory T cells in tumor imm