𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Retargeting of human lymphocytes against human ovarian carcinoma cells by bispecific antibodies: from laboratory to clinic

✍ Scribed by Delia Mezzanzanica; Silvana Canevari; Maria I. Colnaghi


Book ID
110572812
Publisher
Springer
Year
1992
Tongue
English
Weight
605 KB
Volume
21
Category
Article
ISSN
0940-5437

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T lymphocytes of 8 patients with ovarian cancer were targeted to the tumor cells using F(ab')2 fragments of a bispecific monoclonal antibody (bsAb), specific for CD3 (a component of the T lymphocyte receptor for antigen) and for the folate receptor MOv I 8 (overexpressed by ovarian carcinoma cells)