✦ LIBER ✦

Retargeting of adenoviral vectors to neurons using the HC fragment of tetanus toxin

✍ Scribed by Schneider, H; Groves, M; Mühle, C; Reynolds, P N; Knight, A; Themis, M; Carvajal, J; Scaravilli, F; Curiel, D T; Fairweather, N F

Book ID: 110038759
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 553 KB
Volume: 7
Category: Article
ISSN: 0969-7128
DOI: 10.1038/sj.gt.3301270

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Neuronal binding of tetanus toxin compar

Neuronal binding of tetanus toxin compared to its ganglioside binding fragment (Hc)

✍ Paul S. Fishman; Deborah A. Parks; Anil J. Patwardhan; Christopher C. Matthews 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 69 KB

Non-viral neuronal gene delivery mediate

Non-viral neuronal gene delivery mediated by the HC fragment of tetanus toxin

✍ Andrew Knight; Jaime Carvajal; Holm Schneider; Charles Coutelle; Sue Chamberlain 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 705 KB

The HC Fragment of Tetanus Toxin forms S

The HC Fragment of Tetanus Toxin forms Stable, Concentration-dependent Dimers via an Intermolecular Disulphide Bond

✍ Omar Qazi; Barbara Bolgiano; Dennis Crane; Dmitri I. Svergun; Petr V. Konarev; Z 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 884 KB

A survival motor neuron:tetanus toxin fr

A survival motor neuron:tetanus toxin fragment C fusion protein for the targeted delivery of SMN protein to neurons

✍ Jonathan W. Francis; Dayse Figueiredo; Johanna C. vanderSpek; Laura M. Ayala; Yo 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 805 KB

Efficacy of DNA vaccines expressing the

Efficacy of DNA vaccines expressing the type F botulinum toxin Hc fragment using different promoters

✍ Amit P. Jathoul; Jane L. Holley; Helen S. Garmory 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 67 KB

Immunization does not interfere with upt

Immunization does not interfere with uptake and transport by motor neurons of the binding fragment of tetanus toxin

✍ Paul S. Fishman; Christopher C. Matthews; Deborah A. Parks; Michael Box; Neil F. 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 99 KB

## Abstract The nontoxic binding domain of tetanus toxin (fragment C or TTC) readily undergoes retrograde axonal transport from an intramuscular injection site. This property has led to investigation of TTC as a possible vector for delivering therapeutic proteins to motor neurons. However, the vast