Restoration of decaying long-term potentiation in the hippocampal formation by stimulation of neuromodulatory nuclei in freely moving rats
โ Scribed by V.L Ezrokhi; V.A Zosimovskii; V.A Korshunov; V.A Markevich
- Book ID
- 117492522
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 219 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0306-4522
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๐ SIMILAR VOLUMES
The ability of the perforant path/dentate granule cell synapse of the hippocampal formation to establish and maintain enhanced levels of synaptic transmission in response to tetanization (longterm potentiation, LTP) was investigated in freely moving rats at 15, 30, and 90 days of age. Measures of 1)
Although the neocortex has generally been considered resistant to the induction of long-term potentiation (LTP), we have recently shown that LTP can be reliably induced in the freely moving rat provided that the stimulation sessions are spaced and repeated. Here, we report that the induction of LTP