Although the neocortex has generally been considered resistant to the induction of long-term potentiation (LTP), we have recently shown that LTP can be reliably induced in the freely moving rat provided that the stimulation sessions are spaced and repeated. Here, we report that the induction of LTP
Cholinergic modulation of neocortical long-term potentiation in the awake, freely moving rat
โ Scribed by Tiffany E Boyd; Christopher Trepel; Ronald J Racine
- Book ID
- 113995351
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 247 KB
- Volume
- 881
- Category
- Article
- ISSN
- 0006-8993
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๐ SIMILAR VOLUMES
The ability of the perforant path/dentate granule cell synapse of the hippocampal formation to establish and maintain enhanced levels of synaptic transmission in response to tetanization (longterm potentiation, LTP) was investigated in freely moving rats at 15, 30, and 90 days of age. Measures of 1)
Long-term potentiation (LTP) or long-term depression (LTD) can be produced in the dentate gyrus (DG) of the hippocampus with high-or low-frequency stimulation trains, respectively. Although LTP can be elicited in a variety of preparations, we know of no reports of LTD unaccompanied by seizure activi