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Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer

โœ Scribed by A. Howell; D.J. DeFriend; R.W. Blamey; J.F. Robertson; P. Walton


Book ID
118558186
Publisher
The Lancet
Year
1995
Tongue
English
Weight
330 KB
Volume
345
Category
Article
ISSN
0140-6736

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Induction of apoptosis by tamoxifen and
โœ Paul A. Ellis; Gloria Saccani-Jotti; Robert Clarke; Stephen R.D. Johnston; Eliza ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 151 KB ๐Ÿ‘ 1 views

Hormonal breast cancer therapies have traditionally been considered cytostatic, but recent pre-clinical data suggest that anti-oestrogens can induce apoptosis. The aim of this study was to assess whether tamoxifen (TAM) and ICI 182780 (ICI) could induce apoptosis in human breast cancer, and whether