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Response to specific anti-oestrogen (ICI182780) in tamoxifen-resistant breast cancer

✍ Scribed by M. Dowsett; S.R.D. Johnston; T.J. Iveson; I.E. Smith


Book ID
118557661
Publisher
The Lancet
Year
1995
Tongue
English
Weight
166 KB
Volume
345
Category
Article
ISSN
0140-6736

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The effects of the anti-estrogens 4-hydroxytamoxifen (OHTam), ICI 164,384 and ICI 182,780 were tested on the MCF-7/LCC2 breast-carcinoma cell line, which grows significantly in the presence of OHTam and serves as a model for studying anti-estrogen resistance of estrogen-receptor-positive breast canc