𝔖 Bobbio Scriptorium
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Response of plant tissue culture to a high shear environment

✍ Scribed by Brian S. Hooker; James M. Lee; Gynheung An

Book ID
103527399
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
626 KB
Volume
11
Category
Article
ISSN
0141-0229

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πŸ“œ SIMILAR VOLUMES

Response of a concentrated monoclonal an
Response of a concentrated monoclonal antibody formulation to high shear
✍ Jared S. Bee; Jennifer L. Stevenson; Bhavya Mehta; Juraj Svitel; Joey Pollastrin πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 124 KB

## Abstract There is concern that shear could cause protein unfolding or aggregation during commercial biopharmaceutical production. In this work we exposed two concentrated immunoglobulin‐G1 (IgG1) monoclonal antibody (mAb, at >100 mg/mL) formulations to shear rates between 20,000 and 250,000 s^βˆ’1