Response variability of human brain tumors to AZQ in tissue culture
โ Scribed by Paul L Kornblith; Louis Rosa; James D Bona; John A Edwards; Nancy Matuzic; Alan Hirschfeld; Calvin Hawkins
- Publisher
- Springer US
- Year
- 1986
- Tongue
- English
- Weight
- 412 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0167-594X
No coin nor oath required. For personal study only.
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Ninety-three patients with primary intracranial brain tumors recurrent after cerebral irradiation were treated with aziridinylbenzoquinone (AZQ; Diaziquone). Twenty-four (26%) had tumor regression lasting a median of 9.2 months. Prior chemotherapy was not significantly associated with tumor regressi
## Abstract For malignant cells cultured from a human astrocytoma, electrophysiological characteristics of the plasma membrane included specific resistivity of 446.82 ยฑ 279.5 ohmยทcm^2^, specific capacitance of 0.758 ยฑ 0.52 microfarads/cm^2^, time constant 0.318ยฑ 0.10 msec. The resting membrane pote