## Racemic gossypol is resolved by HPLC of its amino acid ester Schiff's base derivatives on non-chiral columns. This provides a rapid and accurate method for determination of optical purityon a small scale and, combined with hydrolysis and fractional crystallization, for the preparation of pure g
Resolution of gossypol: Analytical and preparative HPLC
β Scribed by Matlin, S. A. ;Zhou, R.
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 271 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0935-6304
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## Abstract Huperzine A (HupA) and huperzine B (HupB) are two medically important components of __Huperzia serrata__. It is difficult to obtain high yields of the separation from the plant using conventional liquid extraction and chromatography. However, this study has found that RP chromatography