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Resolution of enantiomers of hydroxyeicosatetraenoate derivatives by chiral phase high-pressure liquid chromatography

✍ Scribed by Dan J. Hawkins; Hartmut Kühn; Eric H. Petty; Alan R. Brash

Book ID
107714574
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
522 KB
Volume
173
Category
Article
ISSN
0003-2697

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Enantiomers of terfenadine were resolved by high-performance liquid chromatography (HF'LC) using a chiral stationary phase (CSP) column packed with p-cyclodextrin (p-CD) covalently bound to silica. Separation was achieved in both the reverse phase and normal phase modes. Resolution of enantiomers wa