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Direct resolution of epoxyeicosatrienoic acid enantiomers by chiral-phase high-performance liquid chromatography

✍ Scribed by Ji Y. Zhang; Ian A. Blair


Publisher
Elsevier Science
Year
1994
Weight
376 KB
Volume
657
Category
Article
ISSN
0378-4347

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Resolution of terfenadine enantiomers by
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Enantiomers of terfenadine were resolved by high-performance liquid chromatography (HF'LC) using a chiral stationary phase (CSP) column packed with p-cyclodextrin (p-CD) covalently bound to silica. Separation was achieved in both the reverse phase and normal phase modes. Resolution of enantiomers wa