RESISTIN UPREGULATES ICAM-1, P-SELECTIN AND FRACTALKINE IN HUMAN ENDOTHELIAL CELLS
β Scribed by Manduteanu, I.; Dragomir, E.; Calin, M.; Gan, A.; Stan, D.; Simionescu, M.
- Book ID
- 118636104
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 66 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1567-5688
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π SIMILAR VOLUMES
Endothelial cells, as they normally exist in the vasculature as quiescent cells, perform several functions. In an inflammatory response, endothelial cells are activated to up-regulate a number of genes, including E-selectin (ELAM-l), VCAM-1, ICAM-1, interleukin (IL)-l, IL-8 and plasminogen activator
## Abstract Resistin, firstly reported as an adipocyteβspecific hormone, is suggested to be an important link between obesity and diabetes. Recent studies have suggested an association between resistin and atherogenic processes. The adhesion of circulating monocytes to endothelial cells is a critic